Scientists have discovered a method, following an experiment performed on mice, where you can lose up to 30% of body weight in just one week.
Method by which you can quickly lose weight Photo: Shutterstock
The researchers have genetically changed mice so that they cannot produce the cysteine amino acid and fed them with a completely devoid diet. In just one week, mice lost 30% of their body weight amazingly.
This weight loss is due to an interruption of energy metabolism caused by the exhaustion of coenzyme A, an essential molecule for the transformation of food into energy.
Following the study, it was found that deprivation of cysteine triggers a rapid weight loss.
Published on May 21 in Nature magazine, research shows that the exhaustion of Cysteine throws the body’s metabolism. Without this amino acid, the cells of mice could not effectively transform food into energy. As a result, their body began to burn fat reserves in a quick attempt to deal with energy demand, reports the SCI Tech Daily.
Fundamental change
The study, led by researchers at Nyu Grossman School of Medicine, sheds light on how cells process fuel sources such as carbohydrates and fats. It also highlights the central role of a small molecule called coenzyme a (co). When the levels of cysteine have decreased, the levels of CO also decreased, and for this reason the foods have not been “transformed” into energy.
Coenzyme A is involved in over 100 metabolic reactions and works with about 4% of all enzymes in the body. So far, it has been difficult to study directly, because mice with faulty production of coil do not usually pass the childhood period. But this research offers the first detailed look at how Coa works in adult mice – and what happens when it fails.
“Our surprising discoveries show that low levels of cysteine have triggered a rapid fat loss in our study mice by activating a network of interconnected biological paths“Said the main co -author of the study, Dr. Evgeny Nudler, professor at the Department of Molecular Biochemistry and Pharmacology at Nyu Grossman School of Medicine and researcher of Howard Hughes Medical Institute.
“While the management of weight loss in the clinic remains a future key mission, we are most delighted for the moment by the deep, fundamental aspects of metabolism revealed in this study“Added Dr. Nudler.
The effects of eliminating cysteine on the human body
The current discovery does not even suggest a new approach to weight loss, warns the authors, because cysteine is found in almost all foods. Making a really cysteine -free diet would require patients to consume a specially formulated solution, which would be a challenge for the majority.
In addition, because cysteine is involved in numerous cellular paths, elimination, such as through a drug that inhibits cysteine production, could make organs more vulnerable to daily toxins, including drugs, according to the source.
The study is the first to examine the effects of eliminating cysteine or any of the nine essential amino acids, which must be obtained by nutrition and are necessary for the construction of proteins that make up most enzymes, tissues and signaling molecules of the body. The results showed that the elimination of cysteine from the body of mammals has led to a much greater weight loss than the elimination of any other essential amino acid. In response, the body has resorted to stored lipids (fats) to produce energy.
